TXN2 and CIB4

Data Source:
BioGRID (two hybrid)

		TXN2	CIB4
Description		thioredoxin 2	calcium and integrin binding family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Diastolic blood pressure ( 27841878) FagerstrÓ§m test for nicotine dependence ( 31294817) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Periodontal microbiota ( 22699663) Post bronchodilator FEV1 ( 26634245) Pulse pressure ( 27841878) Response to olanzapine in schizophrenia ( 29503163) Severe aplastic anemia ( 32004448) Systolic blood pressure ( 27841878)
Interacting Genes		79 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 BHLHB9 C11orf49 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B DCTD DDIT3 ETHE1 FAM9B FHL5 FMNL2 GOLGA6L9 GPRASP2 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	7 interacting genes: ATG9A CREB5 MYPOP TACO1 TXN2 VASN ZBTB9
Entrez ID		25828	130106
HPRD ID		07161	18726
Ensembl ID		ENSG00000100348	ENSG00000157884
Uniprot IDs		Q99757	A0PJX0
PDB IDs		1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?
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