TXN2 and STN1

Data Source:
BioGRID (two hybrid)

		TXN2	STN1
Description		thioredoxin 2	STN1 subunit of CST complex
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GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body	Chromosome, Telomeric Region Fibrillar Center Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton CST Complex
	Molecular Function	Protein Binding Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Peptide-methionine (R)-S-oxide Reductase Activity Protein-containing Complex Binding	Single-stranded DNA Binding Protein Binding Telomeric DNA Binding Single-stranded Telomeric DNA Binding
	Biological Process	Sulfur Amino Acid Catabolic Process Response To Hypoxia Glycerol Ether Metabolic Process Response To Oxidative Stress Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Replication
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 30804561) Leukocyte telomere length ( 32109421) Uterine fibroids ( 31488892 30194396) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		79 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 BHLHB9 C11orf49 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B DCTD DDIT3 ETHE1 FAM9B FHL5 FMNL2 GOLGA6L9 GPRASP2 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	19 interacting genes: APP C14orf119 C1orf109 CDK3 GOLGA2 LDLRAP1 LRRK2 MFHAS1 MKRN3 MVP NTAQ1 RCOR3 TEN1 TOLLIP TPP1 TRIML2 TUBGCP4 TXN2 ZDHHC17
Entrez ID		25828	79991
HPRD ID		07161	14872
Ensembl ID		ENSG00000100348	ENSG00000107960
Uniprot IDs		Q99757	Q9H668
PDB IDs		1UVZ 1W4V 1W89	4JOI 4JQF 6W6W
Enriched GO Terms of Interacting Partners?
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