SCAMP1 and DNAJC5

Data Source:
BioGRID (fluorescent resonance energy transfer)

		SCAMP1	DNAJC5
Description		secretory carrier membrane protein 1	DnaJ heat shock protein family (Hsp40) member C5
Image		No pdb structure
GO Annotations	Cellular Component	Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle Synaptic Vesicle Membrane Trans-Golgi Network Membrane Specific Granule Membrane Zymogen Granule Membrane Recycling Endosome Membrane	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Protein Transport Neutrophil Degranulation	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways		Neutrophil degranulation	Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339) Intraocular pressure ( 29785010) Platelet count ( 32888494) Plateletcrit ( 32888494) Triglycerides ( 26780889)	Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		26 interacting genes: ARFIP1 ARFIP2 DNAJC5 EGFR EPS15 GAD2 ITSN1 KRTAP13-1 MTERF3 NDRG4 PBX3 PCYT1A PTPN9 SCAMP2 SLC9A7 SNAP23 SNAP25 SPG21 SYNRG TASOR2 TBRG4 THAP4 TP53 TTPA UBE3A ZMIZ2	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		9522	80331
HPRD ID		06072	08539
Ensembl ID		ENSG00000085365	ENSG00000101152
Uniprot IDs		A0A087WXB0 B4E2V7 O15126	Q6AHX3 Q9H3Z4
PDB IDs			2N04 2N05
Enriched GO Terms of Interacting Partners?
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