RUSC1 and NUDT22

Data Source:
BioGRID (two hybrid)

		RUSC1	NUDT22
Description		RUN and SH3 domain containing 1	nudix hydrolase 22
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GO Annotations	Cellular Component	Nucleus Early Endosome Golgi Apparatus Cytosol Microtubule Postsynaptic Density Microtubule Cytoskeleton Cytoplasmic Vesicle	Nucleoplasm
	Molecular Function	Actin Binding Protein Binding	Protein Binding UDP-sugar Diphosphatase Activity Metal Ion Binding GDP-mannose Hydrolase Activity
	Biological Process	Protein Polyubiquitination
Pathways
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Crohn's disease ( 28067908) Fruit consumption ( 32066663)
Interacting Genes		92 interacting genes: ABHD11 ABHD5 ABI2 AKAP8L ANKS1A APP ATP6V0D2 BPIFA1 C1orf109 CCDC120 CCDC57 CCHCR1 CCNC CDKN2B CMTM6 CREM CRYBA2 CTAG1A CTAG1B DMRT3 DOK6 DTX2 DVL2 EXOC8 EXOSC8 FAM9B FNDC3B GCM2 HMG20A HNRNPF INSC KCTD9 KRTAP19-1 KRTAP19-5 KRTAP6-2 KRTAP8-1 LIMS3 LIMS4 LMO2 MAGEA3 MAGEA6 MAGED1 MED25 MEIS2 MISP MOAP1 MORN3 MYOZ3 N4BP3 NICN1 NTAQ1 NTRK1 NUDT22 OIP5 P4HA3 PFDN5 PIK3R3 PLA2G6 PM20D2 PNMA1 POLR1C PRDM14 PRR35 RBPMS SMARCB1 SMYD1 SOHLH1 SPAG8 STUB1 SUOX TBC1D25 TCHP TEKT4 TENT5B TLE5 TRAPPC6A TRIM55 TRIM63 TRIM73 TSSK3 TTC19 TTC7B UFSP1 VGLL3 WWOX WWP2 ZIC1 ZMYND12 ZNF34 ZNF620 ZNF765 ZNF77	22 interacting genes: ARID5A DDIT4L DNAL4 IKZF5 INCA1 KLHL26 LHX3 RUSC1 SAXO1 TCF4 TLE5 USP54 WDR54 ZBTB33 ZMYND12 ZNF143 ZNF19 ZNF343 ZNF398 ZNF581 ZNF648 ZNF655
Entrez ID		23623	84304
HPRD ID		10206	14434
Ensembl ID		ENSG00000160753	ENSG00000149761
Uniprot IDs		B4DQB8 Q9BVN2	Q9BRQ3
PDB IDs		4GIW	5LF9 5LOR 5LOU 5R50 5R51 5R52 5R53 5R54 5R55 5R56 5R57 5R58 5R59 5R5A 5R5B 5R5C 5R5D 5R5E 5R5F 5R5G 5R5H 5R5I 5R5J 5R5K 5R5L 5R5M 5R5N 5R5O 5R5P 5R5Q 5R5R 5R5S 5RKZ
Enriched GO Terms of Interacting Partners?
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