RUSC1 and TTC7B

Data Source:
BioGRID (two hybrid)

		RUSC1	TTC7B
Description		RUN and SH3 domain containing 1	tetratricopeptide repeat domain 7B
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GO Annotations	Cellular Component	Nucleus Early Endosome Golgi Apparatus Cytosol Microtubule Postsynaptic Density Microtubule Cytoskeleton Cytoplasmic Vesicle	Cytosol Plasma Membrane
	Molecular Function	Actin Binding Protein Binding	Protein Binding
	Biological Process	Protein Polyubiquitination	Phosphatidylinositol Phosphorylation Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Anxiety disorder ( 25390645) Cytomegalovirus antibody response ( 21993531) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Nevus count or cutaneous melanoma ( 30429480) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		92 interacting genes: ABHD11 ABHD5 ABI2 AKAP8L ANKS1A APP ATP6V0D2 BPIFA1 C1orf109 CCDC120 CCDC57 CCHCR1 CCNC CDKN2B CMTM6 CREM CRYBA2 CTAG1A CTAG1B DMRT3 DOK6 DTX2 DVL2 EXOC8 EXOSC8 FAM9B FNDC3B GCM2 HMG20A HNRNPF INSC KCTD9 KRTAP19-1 KRTAP19-5 KRTAP6-2 KRTAP8-1 LIMS3 LIMS4 LMO2 MAGEA3 MAGEA6 MAGED1 MED25 MEIS2 MISP MOAP1 MORN3 MYOZ3 N4BP3 NICN1 NTAQ1 NTRK1 NUDT22 OIP5 P4HA3 PFDN5 PIK3R3 PLA2G6 PM20D2 PNMA1 POLR1C PRDM14 PRR35 RBPMS SMARCB1 SMYD1 SOHLH1 SPAG8 STUB1 SUOX TBC1D25 TCHP TEKT4 TENT5B TLE5 TRAPPC6A TRIM55 TRIM63 TRIM73 TSSK3 TTC19 TTC7B UFSP1 VGLL3 WWOX WWP2 ZIC1 ZMYND12 ZNF34 ZNF620 ZNF765 ZNF77	5 interacting genes: COG6 FAM126A FAM126B RAB3IL1 RUSC1
Entrez ID		23623	145567
HPRD ID		10206	18503
Ensembl ID		ENSG00000160753	ENSG00000165914
Uniprot IDs		B4DQB8 Q9BVN2	Q6PIF1 Q86TV6
PDB IDs		4GIW	5DSE 6BQ1
Enriched GO Terms of Interacting Partners?
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