PSD4 and USP9X

Data Source:
BioGRID (pull down)

		PSD4	USP9X
Description		pleckstrin and Sec7 domain containing 4	ubiquitin specific peptidase 9 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Cleavage Furrow Ruffle Membrane	Nucleus Cytoplasm Cytosol Membrane Growth Cone
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Phospholipid Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Co-SMAD Binding Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Protein Targeting To Peroxisome Cell Cycle Chromosome Segregation Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Cell Migration Protein Ubiquitination Protein Deubiquitination Protein Phosphopantetheinylation BMP Signaling Pathway Regulation Of Circadian Rhythm Cellular Protein Metabolic Process Rhythmic Process Axon Extension Protein Stabilization Cell Division Protein K48-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Demethylation
Pathways			Downregulation of SMAD2/3:SMAD4 transcriptional activity Ub-specific processing proteases Synthesis of active ubiquitin: roles of E1 and E2 enzymes Peroxisomal protein import Peroxisomal protein import Amyloid fiber formation
Drugs
Diseases
GWAS		Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Diastolic blood pressure ( 28548082) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate ( 29403010) Hematocrit ( 32888494 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Red blood cell count ( 32888494 27863252) White blood cell count ( 32888494)	Migraine ( 27322543)
Interacting Genes		2 interacting genes: LDLRAP1 USP9X	25 interacting genes: AFDN ALDH1A3 BCL9 CTNNB1 DCX DVL2 ERG FBXW7 GPSM1 MAP3K5 MCL1 NEAT1 PEX5 PSD4 PTEN RNF115 SMAD2 SMAD4 SMN2 SMURF1 STIL SUMO2 TDRD3 UBC VHL
Entrez ID		23550	8239
HPRD ID		15191	02091
Ensembl ID		ENSG00000125637	ENSG00000124486
Uniprot IDs		Q8NDX1	Q6P468 Q86X58 Q93008
PDB IDs			5VBD 5WCH
Enriched GO Terms of Interacting Partners?
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