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LEPROTL1 and ELOVL4
Data Source:
BioGRID
(two hybrid)
LEPROTL1
ELOVL4
Description
leptin receptor overlapping transcript like 1
ELOVL fatty acid elongase 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endosome
Integral Component Of Membrane
Endoplasmic Reticulum
Integral Component Of Endoplasmic Reticulum Membrane
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
G Protein-coupled Photoreceptor Activity
Fatty Acid Elongase Activity
3-oxo-arachidoyl-CoA Synthase Activity
3-oxo-cerotoyl-CoA Synthase Activity
3-oxo-lignoceronyl-CoA Synthase Activity
Very-long-chain 3-ketoacyl-CoA Synthase Activity
Biological Process
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Negative Regulation Of Protein Localization To Cell Surface
Fatty Acid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Detection Of Visible Light
Fatty Acid Elongation, Saturated Fatty Acid
Sphingolipid Biosynthetic Process
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Pathways
Synthesis of very long-chain fatty acyl-CoAs
Drugs
Omega-3-carboxylic acids
Diseases
Stargardt disease (STGD); Fundus flavimaculatus
GWAS
Aging (
22773346
)
Body mass index (
23669352
)
Chronic obstructive pulmonary disease (
28166215
)
Daytime sleep phenotypes (
27126917
)
Macular thickness (
30535121
)
Partial epilepsies (
20522523
)
Interacting Genes
73 interacting genes:
AGPAT4
ARL13B
CD300C
CD79A
CISD2
CLDN7
CLEC2D
CREB3L1
CYP4F2
EDA
EHHADH
ELOVL4
EMP1
FCER1G
FFAR2
FMO1
GJA5
GJA8
GPR152
GPR42
GPX8
JPH1
KCNJ6
KLRG1
LMBR1
LMNA
LNX1
LPAR3
LRRC4C
MALL
MFSD14B
MSR1
NAT8
ORMDL3
PAQR8
PDZK1IP1
PEX16
PLP1
RBFA
REEP4
REEP6
RNF5
RTP2
SCN3B
SDCBP
SFXN3
SLC16A2
SLC25A46
SLC30A4
SLC35C2
SLC7A1
SMCO4
SPG21
SSMEM1
STING1
STX12
SYNDIG1
TGFA
TMEM11
TMEM14B
TMEM19
TMEM237
TMEM248
TMEM42
TMEM50A
TMEM50B
TMX2
TSNARE1
TSPAN2
TVP23A
VAPA
YIPF2
ZDHHC15
95 interacting genes:
ADGRE2
ANKRD46
APOL3
ATP13A1
BCL2L1
BET1
BIK
BNIP1
BNIP3
BTN2A2
C1GALT1
CCDC167
CCL4L2
CD70
CLCA4
CLDND2
CMTM3
CMTM5
CMTM7
COL4A5
CYB5R3
CYP4F2
ERG28
FA2H
FAM177A1
FAM3C
FAXDC2
FDFT1
FKBP8
FXYD6
GIMAP1
GIMAP5
GOSR2
GPR37L1
GYPA
HMOX1
HMOX2
HSD3B7
IER3IP1
ITGAM
JAGN1
LEPROTL1
LHFPL5
LY6D
MALL
MMP14
NINJ2
ORMDL2
ORMDL3
PKMYT1
PLLP
PLN
PLP1
PTPN1
RAB18
RTP2
SEC22A
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SLC30A3
SLC30A8
SNORC
STX3
SYNDIG1
TECR
TF
TMEM11
TMEM128
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM242
TMEM243
TMEM254
TMEM42
TMEM44
TRARG1
TREX1
TSNARE1
UBE2J1
UNC50
VAMP1
VAMP3
VAMP4
VAMP5
VAPB
YIF1A
YIPF6
ZDHHC21
ZFPL1
Entrez ID
23484
6785
HPRD ID
09551
05697
Ensembl ID
ENSG00000104660
ENSG00000118402
Uniprot IDs
O95214
Q6FHL7
Q9GZR5
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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