ELOVL4 and C1GALT1

Data Source:
BioGRID (two hybrid)

		ELOVL4	C1GALT1
Description		ELOVL fatty acid elongase 4	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Endoplasmic Reticulum Membrane	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding G Protein-coupled Photoreceptor Activity Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity	Protein Binding Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Activity Metal Ion Binding
	Biological Process	Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Detection Of Visible Light Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Angiogenesis Kidney Development O-glycan Processing O-glycan Processing, Core 1 Protein Phosphopantetheinylation Cell Differentiation
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) O-linked glycosylation of mucins
Drugs		Omega-3-carboxylic acids
Diseases		Stargardt disease (STGD); Fundus flavimaculatus
GWAS		Aging ( 22773346) Body mass index ( 23669352) Chronic obstructive pulmonary disease ( 28166215) Daytime sleep phenotypes ( 27126917) Macular thickness ( 30535121) Partial epilepsies ( 20522523)	Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 30224653) Erosive tooth wear (severe vs non-severe) ( 29898447) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Multiple sclerosis (severity) ( 19010793) Night sleep phenotypes ( 27126917) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Serum galactose-deficient IgA1 levels ( 28187132) Smooth-surface caries ( 24556642) Systolic blood pressure ( 26969751) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		95 interacting genes: ADGRE2 ANKRD46 APOL3 ATP13A1 BCL2L1 BET1 BIK BNIP1 BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD70 CLCA4 CLDND2 CMTM3 CMTM5 CMTM7 COL4A5 CYB5R3 CYP4F2 ERG28 FA2H FAM177A1 FAM3C FAXDC2 FDFT1 FKBP8 FXYD6 GIMAP1 GIMAP5 GOSR2 GPR37L1 GYPA HMOX1 HMOX2 HSD3B7 IER3IP1 ITGAM JAGN1 LEPROTL1 LHFPL5 LY6D MALL MMP14 NINJ2 ORMDL2 ORMDL3 PKMYT1 PLLP PLN PLP1 PTPN1 RAB18 RTP2 SEC22A SEC22B SERF1A SERF1B SERP2 SFT2D2 SLC30A3 SLC30A8 SNORC STX3 SYNDIG1 TECR TF TMEM11 TMEM128 TMEM19 TMEM199 TMEM203 TMEM218 TMEM222 TMEM242 TMEM243 TMEM254 TMEM42 TMEM44 TRARG1 TREX1 TSNARE1 UBE2J1 UNC50 VAMP1 VAMP3 VAMP4 VAMP5 VAPB YIF1A YIPF6 ZDHHC21 ZFPL1	30 interacting genes: ANKS6 ARL13B C1GALT1C1 CD79A CPLX4 ELOVL4 FAM209A FAM210B GJA8 GJB1 GJB5 GPR101 GPR151 GPR42 GPRC5D GPX8 LEPROT LEUTX LHFPL5 MUC1 PIGP RETREG3 SLC14A1 SLC1A1 SLC7A14 STX1A TMEM14B TMEM237 TMEM52B XRN1
Entrez ID		6785	56913
HPRD ID		05697	16631
Ensembl ID		ENSG00000118402	ENSG00000106392
Uniprot IDs		Q9GZR5	A0A024RA32 Q9NS00
PDB IDs
Enriched GO Terms of Interacting Partners?
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