LEPROTL1 and TMEM42

Data Source:
BioGRID (two hybrid)

		LEPROTL1	TMEM42
Description		leptin receptor overlapping transcript like 1	transmembrane protein 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Bipolar disorder ( 31043756)
Interacting Genes		73 interacting genes: AGPAT4 ARL13B CD300C CD79A CISD2 CLDN7 CLEC2D CREB3L1 CYP4F2 EDA EHHADH ELOVL4 EMP1 FCER1G FFAR2 FMO1 GJA5 GJA8 GPR152 GPR42 GPX8 JPH1 KCNJ6 KLRG1 LMBR1 LMNA LNX1 LPAR3 LRRC4C MALL MFSD14B MSR1 NAT8 ORMDL3 PAQR8 PDZK1IP1 PEX16 PLP1 RBFA REEP4 REEP6 RNF5 RTP2 SCN3B SDCBP SFXN3 SLC16A2 SLC25A46 SLC30A4 SLC35C2 SLC7A1 SMCO4 SPG21 SSMEM1 STING1 STX12 SYNDIG1 TGFA TMEM11 TMEM14B TMEM19 TMEM237 TMEM248 TMEM42 TMEM50A TMEM50B TMX2 TSNARE1 TSPAN2 TVP23A VAPA YIPF2 ZDHHC15	54 interacting genes: AQP3 AQP6 BDKRB1 CD79A DTX2 EBP EDA ELOVL4 ERGIC3 FAM174A FAM209A GET1 GJA8 GOLM2 GPR152 GPX8 HSD17B11 HSD17B13 LEPROTL1 LHFPL5 LMNA MFF MGAT5B MMD MMGT1 MRM1 MTIF3 NEMP1 PROP1 PSCA RABAC1 RBPMS REEP1 REEP2 RETREG3 RHBDD1 SAR1A SCN3B SEC11C SERINC2 SHISAL1 SLC18A1 SLC34A2 SMIM14 SVOPL TLX3 TM4SF19 TMEM147 TMEM14B TMEM237 TMEM35A TMEM74 VENTX ZDHHC15
Entrez ID		23484	131616
HPRD ID		09551	15540
Ensembl ID		ENSG00000104660	ENSG00000169964
Uniprot IDs		O95214 Q6FHL7	Q69YG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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