LEPROTL1 and SLC25A46

Data Source:
BioGRID (two hybrid)

		LEPROTL1	SLC25A46
Description		leptin receptor overlapping transcript like 1	solute carrier family 25 member 46
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Integral Component Of Membrane	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Localization To Cell Surface	Mitochondrial Membrane Fission
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic sensitization ( 23817571) Asthma ( 31959851 30929738 27182965 31619474 29273806) Asthma (adult onset) ( 31036433 30929738) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Cardiac structure and function ( 19584346) Medication use (adrenergics, inhalants) ( 31015401) Medication use (antihistamines for systemic use) ( 31015401) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355) Uterine fibroid size (maximum volume) ( 30196971)
Interacting Genes		73 interacting genes: AGPAT4 ARL13B CD300C CD79A CISD2 CLDN7 CLEC2D CREB3L1 CYP4F2 EDA EHHADH ELOVL4 EMP1 FCER1G FFAR2 FMO1 GJA5 GJA8 GPR152 GPR42 GPX8 JPH1 KCNJ6 KLRG1 LMBR1 LMNA LNX1 LPAR3 LRRC4C MALL MFSD14B MSR1 NAT8 ORMDL3 PAQR8 PDZK1IP1 PEX16 PLP1 RBFA REEP4 REEP6 RNF5 RTP2 SCN3B SDCBP SFXN3 SLC16A2 SLC25A46 SLC30A4 SLC35C2 SLC7A1 SMCO4 SPG21 SSMEM1 STING1 STX12 SYNDIG1 TGFA TMEM11 TMEM14B TMEM19 TMEM237 TMEM248 TMEM42 TMEM50A TMEM50B TMX2 TSNARE1 TSPAN2 TVP23A VAPA YIPF2 ZDHHC15	16 interacting genes: AQP6 FHL3 FUNDC1 HSD17B11 HSD17B13 LEPROTL1 MFSD14B ODF4 REEP2 REEP4 SLC10A1 SLC10A6 SLC66A2 SLC7A8 SPCS1 VMA21
Entrez ID		23484	91137
HPRD ID		09551	14283
Ensembl ID		ENSG00000104660	ENSG00000164209
Uniprot IDs		O95214 Q6FHL7	B4DY98 Q96AG3
PDB IDs
Enriched GO Terms of Interacting Partners?
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