TRAK1 and CDC5L

Data Source:
BioGRID (two hybrid)

		TRAK1	CDC5L
Description		trafficking kinesin protein 1	cell division cycle 5 like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Early Endosome Cell Cortex Dendrite Cytoplasmic Vesicle Mitochondrial Membrane Axon Cytoplasm	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Cytoplasm Membrane Nuclear Speck Perinuclear Region Of Cytoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Signaling Receptor Binding Protein Binding Myosin Binding GABA Receptor Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Protein Phosphatase 1 Binding Protein Kinase Binding Leucine Zipper Domain Binding WD40-repeat Domain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Endosome To Lysosome Transport Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Anterograde Axonal Transport Of Mitochondrion	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome DNA Repair Regulation Of Transcription By RNA Polymerase II Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Interleukin-2 Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To Wortmannin Cellular Response To Nerve Growth Factor Stimulus Cellular Response To Prolactin
Pathways		Signaling by BRAF and RAF fusions	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 28552196) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 32439900) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Alzheimer disease and age of onset ( 26830138) Chin dimples ( 27182965) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) FEV1 ( 30804560) Height ( 28552196) Ischemic stroke ( 26089329) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965) Monobrow ( 27182965) Nose morphology ( 29921221) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis ( 22763110) Osteoarthritis of the hand ( 28855172) Stroke (ischemic) ( 22941190) Trunk fat mass adjusted for trunk lean mass ( 32239398)
Interacting Genes		12 interacting genes: BLOC1S6 BYSL CDC5L CDK6 ENKD1 HGS MAGEB4 OGT POLR2A SKIL TRAF3IP1 ZNF232	94 interacting genes: AKAP6 AKAP9 BICRAL CALM1 CCDC136 CDC42 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HNRNPM HOOK1 KALRN KANK2 KANSL1 KDM1A KIF3C KIF5B KRT18 LDOC1 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MIR106B MIR107 MIR143 MIR200B MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR429 MIRLET7A2 MIRLET7D MIRLET7E MIRLET7G MIRLET7I MTUS2 MYT1L ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 SYNPO TP53BP2 TRAF3IP1 TRAK1 TRIO TTF2 TXLNA USHBP1 VPS52 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZRANB1 ZSCAN1
Entrez ID		22906	988
HPRD ID		09732	04184
Ensembl ID		ENSG00000182606	ENSG00000096401
Uniprot IDs		A0A087X0N0 B7Z218 B7ZAE5 Q9UPV9	Q99459
PDB IDs			2DIM 2DIN 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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