TRAK1 and BLOC1S6

Data Source:
BioGRID (two hybrid)

		TRAK1	BLOC1S6
Description		trafficking kinesin protein 1	biogenesis of lysosomal organelles complex 1 subunit 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Early Endosome Cell Cortex Dendrite Cytoplasmic Vesicle Mitochondrial Membrane Axon Cytoplasm	Cytoplasm Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex Presynapse Axon Cytoplasm
	Molecular Function	Signaling Receptor Binding Protein Binding Myosin Binding GABA Receptor Binding	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Endosome To Lysosome Transport Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Anterograde Axonal Transport Of Mitochondrion	Anterograde Axonal Transport Synaptic Vesicle Docking Neuron Projection Development Melanosome Transport Melanosome Organization Endosome To Melanosome Transport Intracellular Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation
Pathways		Signaling by BRAF and RAF fusions	Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Body mass index ( 28552196) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 32439900) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		12 interacting genes: BLOC1S6 BYSL CDC5L CDK6 ENKD1 HGS MAGEB4 OGT POLR2A SKIL TRAF3IP1 ZNF232	49 interacting genes: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 C4orf46 CCDC136 CCDC22 CCHCR1 CCR2 CDK5R1 CEP44 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 INSYN1 KRT13 KRT72 LURAP1 MED21 MLPH NDC80 NDN NTAQ1 NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 RINT1 SKA1 SLC4A1 SMN1 SMN2 SNAPIN STX11 STX12 STX1A SYCE3 TPM1 TPM3 TRAK1 WASHC3
Entrez ID		22906	26258
HPRD ID		09732	16055
Ensembl ID		ENSG00000182606	ENSG00000104164
Uniprot IDs		A0A087X0N0 B7Z218 B7ZAE5 Q9UPV9	B3KY40 H3BST1 Q9UL45
PDB IDs
Enriched GO Terms of Interacting Partners?
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