TRAK1 and TRAF3IP1

Data Source:
BioGRID (two hybrid)

		TRAK1	TRAF3IP1
Description		trafficking kinesin protein 1	TRAF3 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Early Endosome Cell Cortex Dendrite Cytoplasmic Vesicle Mitochondrial Membrane Axon Cytoplasm	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Ciliary Base
	Molecular Function	Signaling Receptor Binding Protein Binding Myosin Binding GABA Receptor Binding	Protein Binding Microtubule Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein O-linked Glycosylation Protein Targeting Endosome To Lysosome Transport Neurogenesis Vesicle Transport Along Microtubule Mitochondrion Distribution Anterograde Axonal Transport Of Mitochondrion	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type I Interferon Production Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization
Pathways		Signaling by BRAF and RAF fusions	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Body mass index ( 28552196) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) PR interval ( 32439900) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		12 interacting genes: BLOC1S6 BYSL CDC5L CDK6 ENKD1 HGS MAGEB4 OGT POLR2A SKIL TRAF3IP1 ZNF232	29 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SGF29 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC
Entrez ID		22906	26146
HPRD ID		09732	09571
Ensembl ID		ENSG00000182606	ENSG00000204104
Uniprot IDs		A0A087X0N0 B7Z218 B7ZAE5 Q9UPV9	Q8TDR0
PDB IDs			2EQO
Enriched GO Terms of Interacting Partners?
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