CDC5L and GRB14

  • Data Source:
  • BioGRID (two hybrid)

CDC5L

GRB14

Description cell division cycle 5 like growth factor receptor bound protein 14
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Blood pressure ( 24954895 21572416)
  • Body fat percentage ( 26833246 31453325)
  • Body fat percentage variance ( 31453325)
  • Body mass index ( 29381148 26426971)
  • Body mass index (age>50) ( 26426971)
  • Body mass index x sex x age interaction (4df test) ( 26426971)
  • Coronary artery disease ( 32469254 33020668)
  • Diastolic blood pressure ( 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Fasting blood insulin ( 25631608)
  • Fasting blood insulin (BMI interaction) ( 22581228)
  • Glomerular filtration rate in chronic kidney disease ( 26420894)
  • Glycine levels ( 30837465)
  • HDL cholesterol levels ( 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Hip circumference ( 25673412)
  • Hip circumference adjusted for BMI ( 25673412)
  • Hypertension ( 30487518)
  • Immunoglobulin A vasculitis ( 28698626)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Mean arterial pressure ( 29403010 30487518)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Number of sexual partners ( 30643258)
  • Perceived sweetness of sucrose ( 31005972)
  • Pulse pressure ( 27841878 28739976 30487518)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Response to statin therapy ( 20339536)
  • Sexual dimorphism in anthropometric traits ( 23754948)
  • Systolic blood pressure ( 26390057 28135244 27841878 29403010 28739976 27618447 27618452)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Triglyceride levels ( 32203549 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Type 2 diabetes ( 22885922 24509480 21874001 30297969 29632382 32499647 30718926 28869590)
  • Type 2 diabetes (adjusted for BMI) ( 29632382)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412 28448500)
  • Waist-hip ratio ( 25673412 20935629)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 94 interacting genes: AKAP6 AKAP9 BICRAL CALM1 CCDC136 CDC42 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HNRNPM HOOK1 KALRN KANK2 KANSL1 KDM1A KIF3C KIF5B KRT18 LDOC1 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MIR106B MIR107 MIR143 MIR200B MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR429 MIRLET7A2 MIRLET7D MIRLET7E MIRLET7G MIRLET7I MTUS2 MYT1L ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 SYNPO TP53BP2 TRAF3IP1 TRAK1 TRIO TTF2 TXLNA USHBP1 VPS52 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZRANB1 ZSCAN1 25 interacting genes: CDC5L CHFR DAPK3 EGFR ERBB2 FGFR1 FRS3 GIGYF1 GIGYF2 GOLGA2 HCK IGF1R INSR IRS1 MAP3K14 MET PDGFRA PDGFRB PRKCZ SQSTM1 STK26 TEK TNKS2 TRIM27 TRIM55
Entrez ID 988 2888
HPRD ID 04184 03313
Ensembl ID ENSG00000096401 ENSG00000115290
Uniprot IDs Q99459 Q14449
PDB IDs 2DIM 2DIN 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P 2AUG 2AUH 4K81
Enriched GO Terms of Interacting Partners?
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