TRAF3IP1 and SMC2

Data Source:
BioGRID (two hybrid)

		TRAF3IP1	SMC2
Description		TRAF3 interacting protein 1	structural maintenance of chromosomes 2
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GO Annotations	Cellular Component	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Ciliary Tip Ciliary Base	Nuclear Chromosome Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding	Chromatin Binding Single-stranded DNA Binding Protein Binding ATP Binding
	Biological Process	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type I Interferon Production Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Negative Regulation Of Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization	Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization
Pathways		Intraflagellar transport Intraflagellar transport	Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS		Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Apolipoprotein A1 levels ( 32203549) Basal cell carcinoma ( 31174203) HDL cholesterol levels ( 32203549) Keratinocyte cancer (MTAG) ( 31174203) Oily fish consumption ( 32066663) Orofacial clefts (maternal alcohol consumption interaction) ( 21618603) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042) Pork consumption ( 32066663) Sensorimotor dexterity ( 31596458)
Interacting Genes		29 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SGF29 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC	11 interacting genes: ABCC5 CDC42 DISC1 DNMT3B GULP1 LIG4 NCAPD2 PTEN SMC4 SUMO2 TRAF3IP1
Entrez ID		26146	10592
HPRD ID		09571	09277
Ensembl ID		ENSG00000204104	ENSG00000136824
Uniprot IDs		Q8TDR0	A0A024R158 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1
PDB IDs		2EQO	4U4P
Enriched GO Terms of Interacting Partners?
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