FKBP5 and GLMN

Data Source:
BioGRID (fluorescent resonance energy transfer)

		FKBP5	GLMN
Description		FKBP prolyl isomerase 5	glomulin, FKBP associated protein
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Extracellular Exosome	Cytoplasm Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Heat Shock Protein Binding	Signaling Receptor Binding Hepatocyte Growth Factor Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Inhibitor Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding Response To Bacterium Chaperone-mediated Protein Folding	Vasculogenesis Positive Regulation Of Cytokine Production Neural Tube Closure Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Negative Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Interleukin-2 Production Regulation Of Gene Expression, Epigenetic Negative Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Muscle Cell Differentiation
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) ESR-mediated signaling MECP2 regulates neuronal receptors and channels	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Venous malformations, including: Sporadic venous malformation; Cutaneomucosal venous malformation; Glomuvenous malformation
GWAS		Autoimmune thyroid disease ( 32581359) Birth weight ( 31043758) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Offspring birth weight ( 31043758) White blood cell count ( 27863252)	Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252)
Interacting Genes		14 interacting genes: APP CHUK ESR1 FES GLMN HSF1 HSP90AA1 IKBKE MAPT MCMBP NR2C2 PGR STIP1 USP49	16 interacting genes: BIRC2 BIRC3 EFS FBXW7 FKBP1A FKBP4 FKBP5 HSPB1 MET NSFL1C PEX5 PRDM16 RBX1 RNF7 SKP1 SNAI1
Entrez ID		2289	11146
HPRD ID		04019	03451
Ensembl ID		ENSG00000096060	ENSG00000174842
Uniprot IDs		Q13451 Q2TA84	B4DJ85 Q92990
PDB IDs		1KT0 3O5D 3O5E 3O5F 3O5G 3O5I 3O5J 3O5K 3O5L 3O5M 3O5O 3O5P 3O5Q 3O5R 4DRH 4DRI 4DRK 4DRM 4DRN 4DRO 4DRP 4DRQ 4JFI 4JFJ 4JFK 4JFL 4JFM 4R0X 4TW6 4TW7 4TX0 4W9O 4W9P 4W9Q 5BXJ 5DIT 5DIU 5DIV 5NJX 5OBK 5OMP 6SAF 6TX4 6TX5 6TX6 6TX7 6TX8 6TX9 6TXX	4F52
Enriched GO Terms of Interacting Partners?
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