GLMN and RNF7

Data Source:
BioGRID (pull down)

		GLMN	RNF7
Description		glomulin, FKBP associated protein	ring finger protein 7
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GO Annotations	Cellular Component	Cytoplasm Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Cul3-RING Ubiquitin Ligase Complex Cul4A-RING E3 Ubiquitin Ligase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Cullin-RING Ubiquitin Ligase Complex Cul5-RING Ubiquitin Ligase Complex
	Molecular Function	Signaling Receptor Binding Hepatocyte Growth Factor Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding Ubiquitin-protein Transferase Inhibitor Activity	Copper Ion Binding Protein Binding Zinc Ion Binding NEDD8 Transferase Activity Ubiquitin Protein Ligase Activity NEDD8 Ligase Activity Cullin Family Protein Binding
	Biological Process	Vasculogenesis Positive Regulation Of Cytokine Production Neural Tube Closure Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Negative Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Interleukin-2 Production Regulation Of Gene Expression, Epigenetic Negative Regulation Of T Cell Proliferation Positive Regulation Of Phosphorylation Muscle Cell Differentiation	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Phosphopantetheinylation Post-translational Protein Modification Protein Neddylation Response To Redox State
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Venous malformations, including: Sporadic venous malformation; Cutaneomucosal venous malformation; Glomuvenous malformation
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte percentage of white cells ( 27863252) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Myeloid white cell count ( 27863252)	Hepatitis C induced liver fibrosis ( 22841784) Pelvic organ prolapse (moderate/severe) ( 26545240)
Interacting Genes		16 interacting genes: BIRC2 BIRC3 EFS FBXW7 FKBP1A FKBP4 FKBP5 HSPB1 MET NSFL1C PEX5 PRDM16 RBX1 RNF7 SKP1 SNAI1	43 interacting genes: APOBEC3F APOBEC3G ASB11 BTRC CASP7 CBFB CDC34 CHFR CSNK2A1 CSNK2B CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CYCS ELOB ELOC ERBIN GEM GHR GLMN IKBKG ITM2C MKRN3 MNAT1 NEDD4 NEDD4L PLA2G15 PMAIP1 SOCS3 TRIM46 TRIM8 UBE2C UBE2D1 UBE2D2 UBE2D4 UBE2F UBE2L3 UBE2M UBE2Q1 UBE2S
Entrez ID		11146	9616
HPRD ID		03451	04840
Ensembl ID		ENSG00000174842	ENSG00000114125
Uniprot IDs		B4DJ85 Q92990	Q9UBF6
PDB IDs		4F52	2ECL
Enriched GO Terms of Interacting Partners?
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