YJU2 and JADE1

Data Source:
BioGRID (two hybrid)

		YJU2	JADE1
Description		YJU2 splicing factor homolog	jade family PHD finger 1
Image			No pdb structure
GO Annotations	Cellular Component	U2-type Catalytic Step 1 Spliceosome	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome Cytoplasm Plasma Membrane Nuclear Speck Ciliary Basal Body
	Molecular Function	Protein Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding Metal Ion Binding
	Biological Process	Generation Of Catalytic Spliceosome For First Transesterification Step RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator	Apoptotic Process Negative Regulation Of Cell Growth Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS			Arterial stiffness index ( 31235810) Bone mineral density (total hip) ( 29883787)
Interacting Genes		22 interacting genes: BANP BRAP CCDC57 CEP70 EMILIN1 FRS2 GAS8 GOLGA2 GOLGA6A JADE1 KAT5 LNX2 MAD1L1 MEOX2 REL TFCP2 TRIM15 TRIM21 TRIM27 ZNF143 ZNF526 ZNF829	15 interacting genes: AKT1 CTNNB1 H3C14 H4C1 HMOX2 PFDN1 SEPTIN8 SMN1 TK1 UBE2E1 UBE2H UBE3A VHL YJU2 ZNF148
Entrez ID		55702	79960
HPRD ID		08546	10151
Ensembl ID		ENSG00000105248	ENSG00000077684
Uniprot IDs		Q9BW85	B4E2E2 Q6IE81
PDB IDs		5YZG 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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