ZNF438 and FXR1

Data Source:
BioGRID (two hybrid)

		ZNF438	FXR1
Description		zinc finger protein 438	FMR1 autosomal homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleolus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Costamere Dendritic Spine Dendritic Spine Neck Perinuclear Region Of Cytoplasm Presynapse Glutamatergic Synapse Dendritic Filopodium
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Skeletal Muscle Organ Development Positive Regulation Of Gene Silencing By MiRNA Positive Regulation Of Response To DNA Damage Stimulus
Pathways			Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Congenital left-sided heart lesions (maternal effect) ( 25138779) Heel bone mineral density ( 30598549) Height ( 25429064 31562340) Multiple sclerosis ( 31604244 21833088) Physiological traits ( 31902109) Pulse pressure ( 27841878) Response to fenofibrate (triglyceride levels) ( 27002377) Rheumatoid arthritis ( 30423114 24390342)	Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Metabolite levels ( 23823483) Schizophrenia ( 25056061 19571811 29483656 30285260)
Interacting Genes		68 interacting genes: ACOT7 BACH2 BANP BBC3 BYSL CDCA7L CDK18 CEP19 CYSRT1 DMRT3 DPH3 ESRRG FARS2 FRS3 FXR1 GOLGA2 GOLGA6L9 HAPLN2 KCTD7 KRT40 KRTAP10-1 LGALS14 MAGOHB MCC MDFI MID2 MORF4L1 MORN3 MRPL11 MTUS2 MYLIP MYO15B NEK6 NXF1 PIBF1 PICK1 PIH1D2 PLEKHN1 PNMA1 PRMT7 PSMB1 RABEP1 RECK RPP25 SCNM1 SET SMARCD1 SPANXN2 SSX2IP SUV39H1 SYT17 TBC1D22B TP53BP2 TRAF2 TRAPPC2 TRAPPC2B TRIM50 TSGA10 TSTD2 YES1 ZBTB8A ZNF143 ZNF17 ZNF202 ZNF526 ZNF629 ZNF648 ZRANB1	48 interacting genes: AP1M1 BLK BYSL C1orf35 CBX8 CCDC187 CDC7 CDKL3 CEP126 CRMP1 CSNK2A1 CWF19L2 CYFIP2 DHX15 ELOA ERCC6 ERG28 ESCO2 FAM161A FAM90A1 FBXO4 FMR1 FXR2 GBP2 HSPB1 KIF9 LNX1 LRIF1 LUC7L2 MAGOH MAGOHB MCRS1 MFAP1 PRAM1 PRPF31 PRSS23 SRPK2 STK16 SUFU SYT6 TBC1D22B TCEA2 TRPM1 YES1 ZMAT2 ZNF417 ZNF438 ZNF71
Entrez ID		220929	8087
HPRD ID		11247	02892
Ensembl ID		ENSG00000183621	ENSG00000114416
Uniprot IDs		Q5T427 Q7Z4V0	A0A0F7KYT8 A0A0F7L1S3 P51114
PDB IDs			2CPQ 3KUF 3O8V
Enriched GO Terms of Interacting Partners?
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