ZNF438 and PRMT7

Data Source:
BioGRID (two hybrid)

		ZNF438	PRMT7
Description		zinc finger protein 438	protein arginine methyltransferase 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Fibrillar Center Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Spliceosomal SnRNP Assembly Regulation Of Gene Expression By Genetic Imprinting Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation
Pathways			RMTs methylate histone arginines
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Congenital left-sided heart lesions (maternal effect) ( 25138779) Heel bone mineral density ( 30598549) Height ( 25429064 31562340) Multiple sclerosis ( 31604244 21833088) Physiological traits ( 31902109) Pulse pressure ( 27841878) Response to fenofibrate (triglyceride levels) ( 27002377) Rheumatoid arthritis ( 30423114 24390342)	Birth weight ( 31043758) Body mass index ( 28892062 25673413) Magnesium levels ( 20700443) Offspring birth weight ( 31043758) Refractive error ( 32231278) Schizophrenia ( 31579629) Serum metabolite levels ( 23093944) Weight ( 28552196)
Interacting Genes		68 interacting genes: ACOT7 BACH2 BANP BBC3 BYSL CDCA7L CDK18 CEP19 CYSRT1 DMRT3 DPH3 ESRRG FARS2 FRS3 FXR1 GOLGA2 GOLGA6L9 HAPLN2 KCTD7 KRT40 KRTAP10-1 LGALS14 MAGOHB MCC MDFI MID2 MORF4L1 MORN3 MRPL11 MTUS2 MYLIP MYO15B NEK6 NXF1 PIBF1 PICK1 PIH1D2 PLEKHN1 PNMA1 PRMT7 PSMB1 RABEP1 RECK RPP25 SCNM1 SET SMARCD1 SPANXN2 SSX2IP SUV39H1 SYT17 TBC1D22B TP53BP2 TRAF2 TRAPPC2 TRAPPC2B TRIM50 TSGA10 TSTD2 YES1 ZBTB8A ZNF143 ZNF17 ZNF202 ZNF526 ZNF629 ZNF648 ZRANB1	13 interacting genes: CTCFL DIO3 EIF2S1 H2AC20 H3-5 H3C1 H4C1 MNDA NFKBID POT1 SNRPB ZBTB24 ZNF438
Entrez ID		220929	54496
HPRD ID		11247	15174
Ensembl ID		ENSG00000183621	ENSG00000132600
Uniprot IDs		Q5T427 Q7Z4V0	A0A024R726 Q9NVM4
PDB IDs
Enriched GO Terms of Interacting Partners?
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