ZNF438 and DPH3

Data Source:
BioGRID (two hybrid)

		ZNF438	DPH3
Description		zinc finger protein 438	diphthamide biosynthesis 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	TRNA Wobble Uridine Modification Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Protein Secretion Positive Regulation Of Binding
Pathways			Synthesis of diphthamide-EEF2
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Congenital left-sided heart lesions (maternal effect) ( 25138779) Heel bone mineral density ( 30598549) Height ( 25429064 31562340) Multiple sclerosis ( 31604244 21833088) Physiological traits ( 31902109) Pulse pressure ( 27841878) Response to fenofibrate (triglyceride levels) ( 27002377) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		68 interacting genes: ACOT7 BACH2 BANP BBC3 BYSL CDCA7L CDK18 CEP19 CYSRT1 DMRT3 DPH3 ESRRG FARS2 FRS3 FXR1 GOLGA2 GOLGA6L9 HAPLN2 KCTD7 KRT40 KRTAP10-1 LGALS14 MAGOHB MCC MDFI MID2 MORF4L1 MORN3 MRPL11 MTUS2 MYLIP MYO15B NEK6 NXF1 PIBF1 PICK1 PIH1D2 PLEKHN1 PNMA1 PRMT7 PSMB1 RABEP1 RECK RPP25 SCNM1 SET SMARCD1 SPANXN2 SSX2IP SUV39H1 SYT17 TBC1D22B TP53BP2 TRAF2 TRAPPC2 TRAPPC2B TRIM50 TSGA10 TSTD2 YES1 ZBTB8A ZNF143 ZNF17 ZNF202 ZNF526 ZNF629 ZNF648 ZRANB1	6 interacting genes: ADIPOR1 MEOX2 PIH1D2 RPL8 SERGEF ZNF438
Entrez ID		220929	285381
HPRD ID		11247	16412
Ensembl ID		ENSG00000183621	ENSG00000154813
Uniprot IDs		Q5T427 Q7Z4V0	Q96FX2
PDB IDs			2JR7
Enriched GO Terms of Interacting Partners?
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