FXR1 and TRPM1

Data Source:
BioGRID (two hybrid)

		FXR1	TRPM1
Description		FMR1 autosomal homolog 1	transient receptor potential cation channel subfamily M member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Costamere Dendritic Spine Dendritic Spine Neck Perinuclear Region Of Cytoplasm Presynapse Glutamatergic Synapse Dendritic Filopodium	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity	Cation Channel Activity Calcium Channel Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Skeletal Muscle Organ Development Positive Regulation Of Gene Silencing By MiRNA Positive Regulation Of Response To DNA Damage Stimulus	G Protein-coupled Glutamate Receptor Signaling Pathway Visual Perception Protein Tetramerization Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport Cellular Response To Light Stimulus Cation Transmembrane Transport
Pathways		Signaling by BRAF and RAF fusions	TRP channels
Drugs
Diseases			Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS		Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Metabolite levels ( 23823483) Schizophrenia ( 25056061 19571811 29483656 30285260)	Advanced age-related macular degeneration ( 28813576) Alzheimer's disease (late onset) ( 30820047) Huntington's disease progression ( 28642124) Hypertriglyceridemia ( 23505323) Macular thickness ( 30535121) Refractive error ( 32231278) Response to antipsychotic treatment ( 19721433) Type 2 diabetes ( 30130595)
Interacting Genes		48 interacting genes: AP1M1 BLK BYSL C1orf35 CBX8 CCDC187 CDC7 CDKL3 CEP126 CRMP1 CSNK2A1 CWF19L2 CYFIP2 DHX15 ELOA ERCC6 ERG28 ESCO2 FAM161A FAM90A1 FBXO4 FMR1 FXR2 GBP2 HSPB1 KIF9 LNX1 LRIF1 LUC7L2 MAGOH MAGOHB MCRS1 MFAP1 PRAM1 PRPF31 PRSS23 SRPK2 STK16 SUFU SYT6 TBC1D22B TCEA2 TRPM1 YES1 ZMAT2 ZNF417 ZNF438 ZNF71	1 interacting genes: FXR1
Entrez ID		8087	4308
HPRD ID		02892	04656
Ensembl ID		ENSG00000114416	ENSG00000134160
Uniprot IDs		A0A0F7KYT8 A0A0F7L1S3 P51114	Q7Z4N2
PDB IDs		2CPQ 3KUF 3O8V
Enriched GO Terms of Interacting Partners?
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