FANCG and FANCC

Data Source:
HPRD (in vivo, two hybrid)

		FANCG	FANCC
Description		FA complementation group G	FA complementation group C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Cytosol Plasma Membrane Fanconi Anaemia Nuclear Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Damaged DNA Binding Protein Binding	Protein Binding
	Biological Process	Ovarian Follicle Development DNA Repair Cellular Response To DNA Damage Stimulus Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance
Pathways		Fanconi Anemia Pathway	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases		Fanconi anemia	Fanconi anemia
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)	Birth weight ( 31043758) Hematocrit ( 32888494) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1	54 interacting genes: APC AZIN1 BMPR1A BUB1 CAPN10 CCNA2 CCND1 CDK1 CTBP1 DLC1 DNAJB1 EGFR FANCA FANCD2 FANCE FANCF FANCG FBXW7 GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRAS KRT1 MEOX2 MLH3 MT-ATP6 MUTYH NRAS PDGFRL PIK3CA PMS2 POR PRDX3 PRPF31 PTPN12 PTPRJ RB1 RPL18 RPS3A SMAD4 SPTA1 SPTAN1 SRC STAT1 STMN1 STMN2 TCERG1 TGFBR2 USP14 ZBTB32
Entrez ID		2189	2176
HPRD ID		04262	01967
Ensembl ID		ENSG00000221829	ENSG00000158169
Uniprot IDs		O15287 Q53XM5	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs
Enriched GO Terms of Interacting Partners?
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