FANCG and RTN2

Data Source:
BioGRID (two hybrid)

		FANCG	RTN2
Description		FA complementation group G	reticulon 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Cytosol Plasma Membrane Fanconi Anaemia Nuclear Complex	Endoplasmic Reticulum Intermediate Filament Cell Surface Terminal Cisterna Z Disc Integral Component Of Endoplasmic Reticulum Membrane T-tubule
	Molecular Function	Damaged DNA Binding Protein Binding	Protein Binding
	Biological Process	Ovarian Follicle Development DNA Repair Cellular Response To DNA Damage Stimulus Mitochondrion Organization Spermatid Development Response To Radiation Interstrand Cross-link Repair	Regulation Of Glucose Import Intracellular Protein Transmembrane Transport Negative Regulation Of Amyloid-beta Formation
Pathways		Fanconi Anemia Pathway
Drugs
Diseases		Fanconi anemia
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		44 interacting genes: BRCA2 BRCC3 CAPN1 CBY2 CDK1 COG6 CTBP1 CYP19A1 CYP2E1 DOK5 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 GATA1 GOLGA2 HES1 HGS IHO1 IKZF3 KRT13 KRT19 LNX2 MEOX2 NECAB2 NLGN3 PSMB1 RINT1 RTN2 SAMD3 SSX2IP TADA2A TCEANC TFIP11 TLE5 TPRX1 UIMC1 USHBP1 XRCC3 ZBED1 ZBTB1	1 interacting genes: FANCG
Entrez ID		2189	6253
HPRD ID		04262	04421
Ensembl ID		ENSG00000221829	ENSG00000125744
Uniprot IDs		O15287 Q53XM5	A8K7F2 O75298 Q6GMT0
PDB IDs
Enriched GO Terms of Interacting Partners?
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