ERH and MED31

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ERH	MED31
Description		ERH mRNA splicing and mitosis factor	mediator complex subunit 31
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Midbody Methylosome	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	RNA Binding Protein Binding Methyl-CpG Binding	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleoside Metabolic Process Cell Cycle	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Negative Regulation Of Fibroblast Proliferation Limb Development
Pathways			PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494)	LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		25 interacting genes: APP ATP6V0C CENPH CHTOP CIZ1 COPS6 CSNK2A1 CSNK2A2 CTDP1 CYSRT1 HSPA8 IFITM10 IGSF21 MED31 POLDIP3 PSMA6 RBM48 RPS6KA5 SETDB1 SH3GL2 TASOR2 TLE1 TP53 UNC119 UPRT	59 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1
Entrez ID		2079	51003
HPRD ID		09026	14382
Ensembl ID		ENSG00000100632	ENSG00000108590
Uniprot IDs		A0A024R6D4 P84090	Q9Y3C7
PDB IDs		1W9G 2NML 7CNC
Enriched GO Terms of Interacting Partners?
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