MED31 and HNRNPUL1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED31	HNRNPUL1
Description		mediator complex subunit 31	heterogeneous nuclear ribonucleoprotein U like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex Core Mediator Complex	Nucleus Nucleoplasm
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	RNA Binding Protein Binding Enzyme Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Negative Regulation Of Fibroblast Proliferation Limb Development	MRNA Splicing, Via Spliceosome RNA Processing Response To Virus
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		59 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1	51 interacting genes: BRD7 CRMP1 DMRTB1 DZIP3 EP300 ERG ERG28 EWSR1 GIT2 HNRNPF HNRNPH2 HNRNPH3 IL7R ITCH KLHDC7B MAPK1IP1L MARS1 MED31 NEDD4 NXF1 NXF2 NXF3 PIAS2 PIAS4 PPIL1 PPP1R13B PRMT1 PRMT2 PRPF40A PTEN RBM22 RBM4 RBM4B ROPN1 RPA1 RPA2 SF1 SF3B4 SMN1 SMN2 SNRPB2 SNRPC SORBS3 SRSF9 TGM2 TLX3 TP53 TP53BP2 VPS37C WWP2 ZNF207
Entrez ID		51003	11100
HPRD ID		14382	10428
Ensembl ID		ENSG00000108590	ENSG00000105323
Uniprot IDs		Q9Y3C7	A0A024R0J9 A0A0A0MRA5 A8K3W4 B7Z4B8 Q9BUJ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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