EPB41L1 and GRIA4

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		EPB41L1	GRIA4
Description		erythrocyte membrane protein band 4.1 like 1	glutamate ionotropic receptor AMPA type subunit 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane	Plasma Membrane Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Neuronal Cell Body Dendritic Spine Postsynaptic Membrane Extracellular Vesicle
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding	Amyloid-beta Binding Ionotropic Glutamate Receptor Activity AMPA Glutamate Receptor Activity Ligand-gated Ion Channel Activity Signaling Receptor Activity
	Biological Process	Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization	Glutamate Receptor Signaling Pathway Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway Regulation Of NMDA Receptor Activity
Pathways		Trafficking of AMPA receptors Neurexins and neuroligins	Activation of AMPA receptors Trafficking of AMPA receptors Trafficking of GluR2-containing AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Synaptic adhesion-like molecules
Drugs			Glutamic acid Butabarbital Ethanol Talampanel CX-717 Fluciclovine (18F)
Diseases
GWAS		Height ( 23563607) Hip circumference ( 25673412) Keratinocyte cancer (MTAG) ( 31174203) Refractive error ( 32231278)	Age at first sexual intercourse ( 27089180) Myopia ( 27182965) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Post bronchodilator FEV1 ( 26634245) Refractive error ( 23396134 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		19 interacting genes: AGAP2 APP ARHGAP1 CHRM5 DRD2 DRD3 GRIA1 GRIA4 HSPB1 ITPR1 NR3C1 NUMA1 POT1 SRPK2 STARD13 TERF1 YWHAB YWHAQ YWHAZ	13 interacting genes: ABHD5 ACTN1 CACNG2 CAMK2G EPB41L1 GRIA1 GRIP1 IQGAP1 PICK1 PRKACA PRKCA PRKCG SDCBP
Entrez ID		2036	2893
HPRD ID		04193	00694
Ensembl ID		ENSG00000088367	ENSG00000152578
Uniprot IDs		A0A0C4DH22 B7Z653 Q9H4G0	P48058 Q1WWK6
PDB IDs
Enriched GO Terms of Interacting Partners?
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