EPB41L1 and ARHGAP1

Data Source:
HPRD (two hybrid)

		EPB41L1	ARHGAP1
Description		erythrocyte membrane protein band 4.1 like 1	Rho GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane	Cytoplasm Cytosol Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Sorting Endosome
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding	GTPase Activator Activity Protein Binding SH3 Domain Binding Small GTPase Binding Cadherin Binding
	Biological Process	Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Endosomal Transport Transferrin Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Endocytic Recycling
Pathways		Trafficking of AMPA receptors Neurexins and neuroligins	Rho GTPase cycle
Drugs
Diseases
GWAS		Height ( 23563607) Hip circumference ( 25673412) Keratinocyte cancer (MTAG) ( 31174203) Refractive error ( 32231278)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Bone mineral density (hip) ( 19801982) Experiencing mood swings ( 29500382) Feeling miserable ( 29500382) Feeling nervous ( 29500382) Femoral neck bone mineral density ( 22504420) Neurociticism ( 29500382) Reaction time ( 29844566) Schizophrenia ( 29483656) Suffering from nerves ( 29500382)
Interacting Genes		19 interacting genes: AGAP2 APP ARHGAP1 CHRM5 DRD2 DRD3 GRIA1 GRIA4 HSPB1 ITPR1 NR3C1 NUMA1 POT1 SRPK2 STARD13 TERF1 YWHAB YWHAQ YWHAZ	25 interacting genes: ADGRB2 AGTRAP BNIP2 BNIPL CDC42 CHEK2 EPB41L1 HMGCR HSP90AB1 ITPR1 KIF1B LINC01554 MTNR1B PIK3R1 PTPN11 RAC1 RASA1 RHOA RHOC SH3GL1 SMARCD3 SRC TAX1BP1 TUBA4A WAS
Entrez ID		2036	392
HPRD ID		04193	04108
Ensembl ID		ENSG00000088367	ENSG00000175220
Uniprot IDs		A0A0C4DH22 B7Z653 Q9H4G0	Q07960
PDB IDs			1AM4 1GRN 1OW3 1RGP 1TX4 2NGR 5M6X 5M70 6R3V
Enriched GO Terms of Interacting Partners?
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