TMEM154 and MIP

Data Source:
BioGRID (two hybrid)

		TMEM154	MIP
Description		transmembrane protein 154	major intrinsic protein of lens fiber
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity
	Biological Process		Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport
Pathways			Passive transport by Aquaporins
Drugs			B-nonylglucoside
Diseases
GWAS		Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) Hip circumference ( 28552196) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507) Type 2 diabetes ( 24509480 30054458 29358691 30297969 32499647 30718926 28869590)	Axial length ( 24144296)
Interacting Genes		11 interacting genes: CLCA4 CTSA CYB561D2 FUNDC2 FXYD6 GET3 GYPA MIP SGTA SLC35A4 SMIM1	47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1
Entrez ID		201799	4284
HPRD ID		08719	01098
Ensembl ID		ENSG00000170006	ENSG00000135517
Uniprot IDs		D6R923 Q6P9G4	P30301
PDB IDs
Enriched GO Terms of Interacting Partners?
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