EEF1D and ARHGAP21

Data Source:
BioGRID (pull down)

		EEF1D	ARHGAP21
Description		eukaryotic translation elongation factor 1 delta	Rho GTPase activating protein 21
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Golgi Membrane Golgi Apparatus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Cytoplasmic Vesicle Membrane
	Molecular Function	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding	GTPase Activator Activity Protein Binding
	Biological Process	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Catalytic Activity Cellular Response To Ionizing Radiation	Golgi Organization Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Golgi Localization Establishment Of Golgi Localization Maintenance Of Golgi Location Organelle Transport Along Microtubule
Pathways		Eukaryotic Translation Elongation	Rho GTPase cycle
Drugs
Diseases
GWAS		Schizophrenia ( 31268507)	Advanced age-related macular degeneration ( 26691988) Birth weight ( 31043758) Diisocyanate-induced asthma ( 25918132) Immature fraction of reticulocytes ( 32888494) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Optic disc area ( 31798171) Optic disc size ( 31809533) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		41 interacting genes: ABTB1 ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FKBP6 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 MAP1B NR2F1 POT1 PRKCA RELA RNF40 RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1	7 interacting genes: ARF1 EEF1D PTK2B RHOA SP1 TULP3 ZNF177
Entrez ID		1936	57584
HPRD ID		00560	06445
Ensembl ID		ENSG00000104529	ENSG00000107863
Uniprot IDs		B2RAR6 D3DWK1 P29692	Q5T5U3
PDB IDs		2MVM 2MVN 2N51 5JPO	2DHJ 2J59 2YUY
Enriched GO Terms of Interacting Partners?
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