ARHGAP21

Description		Rho GTPase activating protein 21
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Cytoplasmic Vesicle Membrane
	Molecular Function	GTPase Activator Activity Protein Binding
	Biological Process	Golgi Organization Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Golgi Localization Establishment Of Golgi Localization Maintenance Of Golgi Location Organelle Transport Along Microtubule
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Birth weight ( 31043758) Diisocyanate-induced asthma ( 25918132) Immature fraction of reticulocytes ( 32888494) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Optic disc area ( 31798171) Optic disc size ( 31809533) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Triglyceride levels x loop diuretics use interaction ( 31806883)
Novel Interacting Genes		1 novel interacting genes: ODAD2
Interacting Genes		7 interacting genes: ARF1 EEF1D PTK2B RHOA SP1 TULP3 ZNF177
Entrez ID		57584
HPRD ID		06445
Ensembl ID		ENSG00000107863
Uniprot IDs		Q5T5U3
PDB IDs		2DHJ 2J59 2YUY
Enriched GO Terms of Interacting Partners?
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