EEF1D and CRMP1

Data Source:
HPRD (two hybrid)

		EEF1D	CRMP1
Description		eukaryotic translation elongation factor 1 delta	collapsin response mediator protein 1
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Nucleus Centrosome Spindle Cytosol Growth Cone Midbody Perikaryon
	Molecular Function	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding	Dihydropyrimidinase Activity Protein Binding Filamin Binding Identical Protein Binding
	Biological Process	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Catalytic Activity Cellular Response To Ionizing Radiation	Microtubule Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance Negative Regulation Of Neuron Projection Development Negative Regulation Of Actin Filament Binding
Pathways		Eukaryotic Translation Elongation	CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		Schizophrenia ( 31268507)	Blood trace element (Zn levels) ( 23720494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		41 interacting genes: ABTB1 ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FKBP6 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 MAP1B NR2F1 POT1 PRKCA RELA RNF40 RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1	80 interacting genes: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LRRK2 LSM2 MAP3K20 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RACK1 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1 ZNF24
Entrez ID		1936	1400
HPRD ID		00560	03913
Ensembl ID		ENSG00000104529	ENSG00000072832
Uniprot IDs		B2RAR6 D3DWK1 P29692	B3KT07 B3KV96 E9PD68 Q14194 Q96I11 X5DNI1
PDB IDs		2MVM 2MVN 2N51 5JPO	4B3Z
Enriched GO Terms of Interacting Partners?
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