KCTD7 and ZNF438

Data Source:
BioGRID (two hybrid)

		KCTD7	ZNF438
Description		potassium channel tetramerization domain containing 7	zinc finger protein 438
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Transporter Activity Post-translational Protein Modification Protein Homooligomerization Membrane Hyperpolarization Glutamate Homeostasis	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Aortic root size ( 21223598) Cotinine glucuronidation ( 25293881) Estimated glomerular filtration rate ( 31152163)	Brain morphology (MOSTest) ( 32665545) Congenital left-sided heart lesions (maternal effect) ( 25138779) Heel bone mineral density ( 30598549) Height ( 25429064 31562340) Multiple sclerosis ( 31604244 21833088) Physiological traits ( 31902109) Pulse pressure ( 27841878) Response to fenofibrate (triglyceride levels) ( 27002377) Rheumatoid arthritis ( 30423114 24390342)
Interacting Genes		41 interacting genes: ADAMTSL4 ATXN7L2 BAG4 CUL3 DVL3 EFHC2 GAS2L2 GORASP2 INCA1 INO80B KAT5 KRT75 KRTAP13-3 LNX1 MDFI MEOX1 MEOX2 NIF3L1 NTAQ1 NXF1 PARVG PAX6 PIN1 PPARA PRPF18 PRR22 PSMA1 RAB4A REL TCEA2 TCEANC TERF1 TRIM2 TRIM3 UBC VEZF1 ZNF417 ZNF438 ZNF474 ZNF552 ZNF587	68 interacting genes: ACOT7 BACH2 BANP BBC3 BYSL CDCA7L CDK18 CEP19 CYSRT1 DMRT3 DPH3 ESRRG FARS2 FRS3 FXR1 GOLGA2 GOLGA6L9 HAPLN2 KCTD7 KRT40 KRTAP10-1 LGALS14 MAGOHB MCC MDFI MID2 MORF4L1 MORN3 MRPL11 MTUS2 MYLIP MYO15B NEK6 NXF1 PIBF1 PICK1 PIH1D2 PLEKHN1 PNMA1 PRMT7 PSMB1 RABEP1 RECK RPP25 SCNM1 SET SMARCD1 SPANXN2 SSX2IP SUV39H1 SYT17 TBC1D22B TP53BP2 TRAF2 TRAPPC2 TRAPPC2B TRIM50 TSGA10 TSTD2 YES1 ZBTB8A ZNF143 ZNF17 ZNF202 ZNF526 ZNF629 ZNF648 ZRANB1
Entrez ID		154881	220929
HPRD ID		13770	11247
Ensembl ID		ENSG00000243335	ENSG00000183621
Uniprot IDs		A0A024RDN7 Q96MP8	Q5T427 Q7Z4V0
PDB IDs
Enriched GO Terms of Interacting Partners?
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