CTNNA1 and ARMC8

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CTNNA1	ARMC8
Description		catenin alpha 1	armadillo repeat containing 8
Image			No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Catenin Complex Flotillin Complex Lamellipodium Cell Junction Intracellular Membrane-bounded Organelle	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Intracellular Membrane-bounded Organelle Tertiary Granule Lumen
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Vinculin Binding Identical Protein Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding	Protein Binding
	Biological Process	Ovarian Follicle Development Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Neuroblast Proliferation Aging Male Gonad Development Gap Junction Assembly Cell Migration Axon Regeneration Adherens Junction Organization Cellular Protein Localization Odontogenesis Of Dentin-containing Tooth Apical Junction Assembly Response To Estrogen Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Neutrophil Degranulation
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability Myogenesis Myogenesis RHO GTPases activate IQGAPs	Neutrophil degranulation
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Malaria ( 31844061) Schizophrenia ( 25056061)	Mean spheric corpuscular volume ( 32888494)
Interacting Genes		52 interacting genes: ACTN1 AFDN AJUBA AKT1 ALDOB APC APP ARMC8 BAAT CA9 CCDC180 CDC42 CDH1 CDH15 CDH2 CDH3 CDH5 CSNK2A1 CTBP1 CTNNB1 CTSV DLG1 F2RL1 FBP1 FBP2 FRAT2 HRAS HSD17B3 JUP LRATD2 MAP2K1 MTNR1A MTNR1B NANS OBI1 PKD1 PSEN1 SASH1 SFRP2 SFRP4 SMAD1 SPTAN1 SPTBN1 STX17 TDRD7 TJP1 TJP2 UBE2I VCL ZGPAT ZNF189 ZNF510	8 interacting genes: CIB3 CTNNA1 GID8 MAEA STX6 TCF12 TNNT1 ZMYND12
Entrez ID		1495	25852
HPRD ID		00285	09992
Ensembl ID		ENSG00000044115	ENSG00000114098
Uniprot IDs		A0A384MDY0 B4DKT9 B4DU00 G3XAM7 P35221	B7Z637 Q8IUR7
PDB IDs		1H6G 4EHP 4IGG 6UPV 6V2O 6V2P
Enriched GO Terms of Interacting Partners?
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