ARMC8 and MAEA

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ARMC8	MAEA
Description		armadillo repeat containing 8	macrophage erythroblast attacher, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Intracellular Membrane-bounded Organelle Tertiary Granule Lumen	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix GID Complex
	Molecular Function	Protein Binding	Actin Binding Ubiquitin-protein Transferase Activity Metal Ion Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Neutrophil Degranulation	Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Protein Ubiquitination Negative Regulation Of Myeloid Cell Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Erythrocyte Maturation Negative Regulation Of Gluconeogenesis Cell Division
Pathways		Neutrophil degranulation
Drugs			Tetrachlorodecaoxide
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494)	Obesity-related traits ( 23251661) Pulse pressure ( 30224653) Type 2 diabetes ( 30297969 26818947 23945395 32499647 22158537 30718926 28869590)
Interacting Genes		8 interacting genes: CIB3 CTNNA1 GID8 MAEA STX6 TCF12 TNNT1 ZMYND12	12 interacting genes: ARMC8 GID4 GID8 MKLN1 MYOC RANBP10 RMND5A UBE2D2 UBE2D3 UBE2H UBE2R2 YPEL5
Entrez ID		25852	10296
HPRD ID		09992	08427
Ensembl ID		ENSG00000114098	ENSG00000090316
Uniprot IDs		B7Z637 Q8IUR7	B3KRN7 B4DJP8 B4DQT1 B4DVN3 D6RIB6 Q7L5Y9
PDB IDs
Enriched GO Terms of Interacting Partners?
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