ARMC8 and STX6

Data Source:
BioGRID (two hybrid)

		ARMC8	STX6
Description		armadillo repeat containing 8	syntaxin 6
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol GID Complex Specific Granule Lumen Intracellular Membrane-bounded Organelle Tertiary Granule Lumen	Golgi Membrane Nucleoplasm Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Integral Component Of Membrane Clathrin-coated Vesicle Integral Component Of Synaptic Vesicle Membrane SNARE Complex Trans-Golgi Network Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Neutrophil Degranulation	Intracellular Protein Transport Vesicle Fusion Endosome Organization Synaptic Vesicle To Endosome Fusion Endocytic Recycling Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking Golgi Ribbon Formation Regulation Of Cellular Protein Localization
Pathways		Neutrophil degranulation	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Creutzfeldt-Jakob disease (sporadic) ( 32949544) Menopause (age at onset) ( 26414677) Progressive supranuclear palsy ( 30089514 21685912) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: CIB3 CTNNA1 GID8 MAEA STX6 TCF12 TNNT1 ZMYND12	35 interacting genes: AQP6 ARMC8 DNAJC5 EBP EEA1 FAM210B GOLM2 GOPC LIME1 LMNA MARCHF2 MEOX2 MMGT1 MTERF2 MTIF3 NAPB PSMA3 PTPN9 SCN3B SNAP23 SNAP29 STOM STX16 STX1A STX2 STX4 STX7 TIMMDC1 TMEM14B TMEM205 TMEM86B TMEM9 VAMP4 VPS11 VPS18
Entrez ID		25852	10228
HPRD ID		09992	07231
Ensembl ID		ENSG00000114098	ENSG00000135823
Uniprot IDs		B7Z637 Q8IUR7	O43752
PDB IDs			2NPS 4J2C
Enriched GO Terms of Interacting Partners?
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