PLEKHA7 and B9D2

Data Source:
BioGRID (two hybrid)

		PLEKHA7	B9D2
Description		pleckstrin homology domain containing A7	B9 domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Zonula Adherens Cell Junction Pore Complex Extracellular Exosome	Nucleus Centrosome Cytosol Membrane MKS Complex Ciliary Basal Body
	Molecular Function	Protein Binding Delta-catenin Binding	Protein Binding Gamma-tubulin Binding
	Biological Process	Cell-cell Adhesion Mediated By Cadherin Zonula Adherens Maintenance Pore Complex Assembly Epithelial Cell-cell Adhesion	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Coronary artery disease ( 29212778) Diastolic blood pressure ( 19430479 27841878 28739976 27618452) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary angle closure) ( 22922875 27064256) Intraocular pressure ( 29617998 29785010 31959993 30054594) Macular thickness ( 30535121) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Microalbuminuria in type 1 diabetes ( 31537649) Systolic blood pressure ( 19430479 27841878 28739976 27618452 30578418) Systolic blood pressure change trajectories ( 27980656) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 32469254 29212778) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)
Interacting Genes		20 interacting genes: B9D2 CCHCR1 CCNDBP1 FAM228A GRB2 HOMEZ HSF2BP IGFBP6 IGFL2 LZTS1 NEK6 PIBF1 PICK1 PPL RDH12 RHOH STMN3 TRAF4 TSGA10 ZMAT5	8 interacting genes: ALKBH7 P4HA3 PLEKHA7 PPP1R32 QARS1 SPAG8 TLX3 VPS25
Entrez ID		144100	80776
HPRD ID		15142	14613
Ensembl ID		ENSG00000166689	ENSG00000123810
Uniprot IDs		E9PKC0 Q6IQ23	Q9BPU9
PDB IDs
Enriched GO Terms of Interacting Partners?
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