B9D2 and P4HA3

Data Source:
BioGRID (two hybrid)

		B9D2	P4HA3
Description		B9 domain containing 2	prolyl 4-hydroxylase subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Membrane MKS Complex Ciliary Basal Body	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding Gamma-tubulin Binding	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding
	Biological Process	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 32469254 29212778) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)	Hippocampal atrophy ( 25625606)
Interacting Genes		8 interacting genes: ALKBH7 P4HA3 PLEKHA7 PPP1R32 QARS1 SPAG8 TLX3 VPS25	50 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1orf112 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZBTB7B ZC3H12A
Entrez ID		80776	283208
HPRD ID		14613	16413
Ensembl ID		ENSG00000123810	ENSG00000149380
Uniprot IDs		Q9BPU9	Q7Z4N8
PDB IDs
Enriched GO Terms of Interacting Partners?
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