PLEKHA7 and HOMEZ

Data Source:
BioGRID (two hybrid)

		PLEKHA7	HOMEZ
Description		pleckstrin homology domain containing A7	homeobox and leucine zipper encoding
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Zonula Adherens Cell Junction Pore Complex Extracellular Exosome	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding Delta-catenin Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
	Biological Process	Cell-cell Adhesion Mediated By Cadherin Zonula Adherens Maintenance Pore Complex Assembly Epithelial Cell-cell Adhesion	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Coronary artery disease ( 29212778) Diastolic blood pressure ( 19430479 27841878 28739976 27618452) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary angle closure) ( 22922875 27064256) Intraocular pressure ( 29617998 29785010 31959993 30054594) Macular thickness ( 30535121) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Microalbuminuria in type 1 diabetes ( 31537649) Systolic blood pressure ( 19430479 27841878 28739976 27618452 30578418) Systolic blood pressure change trajectories ( 27980656) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878)
Interacting Genes		20 interacting genes: B9D2 CCHCR1 CCNDBP1 FAM228A GRB2 HOMEZ HSF2BP IGFBP6 IGFL2 LZTS1 NEK6 PIBF1 PICK1 PPL RDH12 RHOH STMN3 TRAF4 TSGA10 ZMAT5	114 interacting genes: ACTR10 AEN ANKRD11 ANKRD2 ARHGAP9 ASB6 AXIN1 BIVM BYSL C2orf42 CBX8 CCDC13 CCDC187 CCHCR1 CCNK CDC7 CENPS CENPS-CORT CFAP206 CTNNA3 DEF6 DGCR6 DHX16 DNTTIP1 EBF1 EIF4E2 ELOA ENKD1 FAM90A1 FARS2 GAS8 GFAP GPANK1 GRB2 HOXC8 HSF2BP IL16 INO80B JAKMIP2 KIFC3 KPNA2 LENG1 LGALS4 LMO1 LMO3 LNX1 LRRC7 LSM4 MAD2L1BP MAFG MAPK1 MED18 MORF4L2 MOS MRPL11 NCK1 NCK2 NEIL2 NEK6 NXF1 OSGIN1 PARVG PHF1 PHF19 PIBF1 PIN1 PLEKHA7 POLDIP3 PRKAA1 PRKAA2 PRPF18 PSMA1 RASL10A RBM39 RNF8 RPGR RPL9 RPP25 RPS25 SCNM1 SDCBP SEC23A SH3RF2 SMARCB1 SMARCD1 SMYD1 SNRPB2 SUMO2 SUMO3 TARS2 TBC1D30 TCEA2 TCEANC TEAD4 TLE5 TRAF4 TSGA10IP TXK USF1 VEZF1 VPS9D1 ZBTB25 ZBTB7A ZMYND19 ZNF165 ZNF250 ZNF280C ZNF35 ZNF417 ZNF580 ZNF629 ZNF688 ZNF76 ZSCAN5B
Entrez ID		144100	57594
HPRD ID		15142	12167
Ensembl ID		ENSG00000166689	ENSG00000215271
Uniprot IDs		E9PKC0 Q6IQ23	Q8IX15
PDB IDs			2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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