PLEKHA7 and STMN3

Data Source:
BioGRID (two hybrid)

		PLEKHA7	STMN3
Description		pleckstrin homology domain containing A7	stathmin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Centrosome Cytosol Zonula Adherens Cell Junction Pore Complex Extracellular Exosome	Cytoplasm Golgi Apparatus Cytosol Growth Cone Neuron Projection
	Molecular Function	Protein Binding Delta-catenin Binding	Protein Binding Tubulin Binding Protein Domain Specific Binding
	Biological Process	Cell-cell Adhesion Mediated By Cadherin Zonula Adherens Maintenance Pore Complex Assembly Epithelial Cell-cell Adhesion	Microtubule Depolymerization Nervous System Development Regulation Of Microtubule Polymerization Or Depolymerization Cytoplasmic Microtubule Organization Neuron Projection Development Negative Regulation Of Rac Protein Signal Transduction Regulation Of GTPase Activity Regulation Of Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 21909110) Blood protein levels ( 30072576 29875488) Body mass index ( 26426971) Coronary artery disease ( 29212778) Diastolic blood pressure ( 19430479 27841878 28739976 27618452) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary angle closure) ( 22922875 27064256) Intraocular pressure ( 29617998 29785010 31959993 30054594) Macular thickness ( 30535121) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Microalbuminuria in type 1 diabetes ( 31537649) Systolic blood pressure ( 19430479 27841878 28739976 27618452 30578418) Systolic blood pressure change trajectories ( 27980656) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Mean corpuscular hemoglobin ( 32888494) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		20 interacting genes: B9D2 CCHCR1 CCNDBP1 FAM228A GRB2 HOMEZ HSF2BP IGFBP6 IGFL2 LZTS1 NEK6 PIBF1 PICK1 PPL RDH12 RHOH STMN3 TRAF4 TSGA10 ZMAT5	27 interacting genes: ANKRD11 C1orf109 CARD9 CLIC3 EXOC8 GLP1R GPANK1 HGS KAT5 KIFC3 KRT34 LTB4R2 MIPOL1 MKRN3 MNS1 NKX3-1 P4HA3 PLEKHA7 POLR1C SMARCD1 SPCS2 TBC1D21 TRIM69 TRPC5 TXLNB UBQLN1 ZNF76
Entrez ID		144100	50861
HPRD ID		15142	16324
Ensembl ID		ENSG00000166689	ENSG00000197457
Uniprot IDs		E9PKC0 Q6IQ23	Q9NZ72
PDB IDs
Enriched GO Terms of Interacting Partners?
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