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TMEM182 and CLDN5
Data Source:
BioGRID
(two hybrid)
TMEM182
CLDN5
Description
transmembrane protein 182
claudin 5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Membrane
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Apicolateral Plasma Membrane
Cell Junction
Cortical Actin Cytoskeleton
Tight Junction
Molecular Function
Protein Binding
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Biological Process
Outflow Tract Morphogenesis
Cell-cell Junction Assembly
Cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Learning
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Positive Regulation Of Protein Binding
Maintenance Of Blood-brain Barrier
Negative Regulation Of Vascular Permeability
Roof Of Mouth Development
Face Morphogenesis
Bicellular Tight Junction Assembly
Tight Junction Assembly
Positive Regulation Of Establishment Of Endothelial Barrier
Positive Regulation Of Bicellular Tight Junction Assembly
Establishment Of Blood-retinal Barrier
Regulation Of Bicellular Tight Junction Assembly
Pathways
Tight junction interactions
RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Age at first sexual intercourse (
27089180
)
Blood pressure (
24903457
)
Blood pressure (anthropometric measures interaction) (
24903457
)
Chromium levels (
26025379
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
General risk tolerance (MTAG) (
30643258
)
Night sleep phenotypes (
27126917
)
Number of sexual partners (
30643258
)
Photic sneeze reflex (
27182965
)
PR interval (
30046033
32439900
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking initiation (
30617275
)
Smoking initiation (ever regular vs never regular) (
30679032
)
Smoking status (ever vs never smokers) (
30643258
)
Interacting Genes
15 interacting genes:
CLDN5
FNDC9
GJA8
GPR42
KLRC1
MALL
MS4A3
PLP1
SMIM3
SUSD3
SYNE4
TMEM140
TMEM218
TMEM31
TSPAN12
40 interacting genes:
AQP1
BTNL8
CCDC167
CLDN3
CLRN2
CNPY3
CORIN
CTRL
CXCL9
CYB561A3
EFNA5
EHHADH
ERG28
ERMP1
FXYD6-FXYD2
GYPA
LAT
LHFPL5
MIP
MPDZ
PLP2
PLPPR2
PMP22
RPRM
SFTPC
SGCG
SLC35B4
SMIM3
TECR
TF
TJP1
TMEM128
TMEM140
TMEM14C
TMEM182
TMEM190
TMEM222
TSPAN2
VAMP5
YIPF1
Entrez ID
130827
7122
HPRD ID
08698
03654
Ensembl ID
ENSG00000170417
ENSG00000184113
Uniprot IDs
Q6ZP80
D3DX19
O00501
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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