C20orf85 and KLHL2

		C20orf85	KLHL2
Description		chromosome 20 open reading frame 85	kelch like family member 2
Image		No pdb structure
GO Annotations	Cellular Component		Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Actin Binding Protein Binding Identical Protein Binding
	Biological Process		Protein Ubiquitination Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Obesity-related traits ( 23251661)	Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		22 interacting genes: ACTN3 ALKBH7 ASPG CABP2 CACNB3 CASK CNOT2 DTX2 EFHC1 FHL2 KLHL2 KLHL20 KRTAP19-6 KRTAP3-1 KRTAP6-2 KRTAP8-1 LCN2 MAD2L2 OIP5 PFDN5 RBPMS TTC19	31 interacting genes: ACTC1 BCAM BYSL C20orf85 CCDC43 CDC37 CLK2 CUL3 CWC22 ELOA KEAP1 KLHL12 KLHL3 MFAP1 NAP1L2 NTAQ1 PADI6 PIBF1 POLR3C SDCBP TMA16 TNPO2 TRIM50 TXNDC12 UBE2C UBE2D1 UBE2I UCK1 WNK1 WNK4 ZNF114
Entrez ID		128602	11275
HPRD ID		12787	09311
Ensembl ID		ENSG00000124237	ENSG00000109466
Uniprot IDs		Q9H1P6	B4DFZ5 E9PEX9 O95198
PDB IDs			2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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