MRPL10 and KLHL12

Data Source:
BioGRID (two hybrid)

		MRPL10	KLHL12
Description		mitochondrial ribosomal protein L10	kelch like family member 12
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Large Ribosomal Subunit Ribonucleoprotein Complex	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Translation Ribosome Biogenesis Mitochondrial Translational Elongation Mitochondrial Translational Termination	Protein Monoubiquitination Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Degradation of DVL
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Asthma ( 31619474) Body mass index ( 26426971)
Interacting Genes		8 interacting genes: ACTN2 APP FAM9B KLHL12 PNMA1 REL TCF4 USP22	62 interacting genes: ARAF ARRDC1 ATXN1 BAG6 BCL6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL1 DVL2 DVL3 FAM90A1 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL24 KLHL3 LNPK LNX1 MAPRE1 MED25 MED28 MPP1 MRPL10 MTNR1A MYO15B NDC80 NTAQ1 PDGFRB PEA15 PEF1 PLEKHA4 PNKP PRR13 RGL3 RIN1 RIT1 RNF4 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TCEANC TTBK2 UBE2I VEGFB VTA1 ZBP1 ZBTB4
Entrez ID		124995	59349
HPRD ID		14738	13925
Ensembl ID		ENSG00000159111	ENSG00000117153
Uniprot IDs		Q7Z7H8	Q53G59 Q9H7R2
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG	2VPJ 6TTK 6V7O
Enriched GO Terms of Interacting Partners?
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