OLIG1 and SH2D1A

Data Source:
BioGRID (two hybrid)

		OLIG1	SH2D1A
Description		oligodendrocyte transcription factor 1	SH2 domain containing 1A
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Oligodendrocyte Development Neuron Differentiation Neuron Fate Commitment	Adaptive Immune Response Humoral Immune Response Cellular Defense Response Cell-cell Signaling Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases			Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
GWAS
Interacting Genes		15 interacting genes: CACNA1A DOK4 DOK5 GRB2 HSH2D MRPL12 NCK1 NUMB PSMD14 PTPN6 RASA1 SH2D1A SH2D4A SHD STAT5A	32 interacting genes: AR ARHGEF6 ARHGEF7 ATF3 CCDC74A CD84 DOK1 EGFR ERBB2 ERBB3 ERBB4 FYB1 FYN GRB2 KIT LCK LETMD1 LHX3 LHX4 LY9 MAPK11 MAPK14 MET NCK1 NGEF OLIG1 PTK2 SLAMF1 SLAMF6 SLAMF7 TNK2 ZNHIT1
Entrez ID		116448	4068
HPRD ID		07333	02390
Ensembl ID		ENSG00000184221	ENSG00000183918
Uniprot IDs		Q8TAK6	O60880
PDB IDs			1D1Z 1D4T 1D4W 1KA6 1KA7 1M27
Enriched GO Terms of Interacting Partners?
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