LYPLA2 and MED31

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LYPLA2	MED31
Description		lysophospholipase 2	mediator complex subunit 31
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Stack Cytosol Extracellular Exosome	Ubiquitin Ligase Complex Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Lysophospholipase Activity Protein Binding Palmitoyl-(protein) Hydrolase Activity Cadherin Binding Carboxylic Ester Hydrolase Activity	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Depalmitoylation Fatty Acid Metabolic Process Axon Guidance Protein Phosphopantetheinylation Acylglycerol Catabolic Process Prostaglandin Catabolic Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Negative Regulation Of Fibroblast Proliferation Limb Development
Pathways		L1CAM interactions	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		5 interacting genes: APP DKC1 INCA1 MED31 SCMH1	59 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1
Entrez ID		11313	51003
HPRD ID		07127	14382
Ensembl ID		ENSG00000011009	ENSG00000108590
Uniprot IDs		A0A140VJC9 O95372	Q9Y3C7
PDB IDs		5SYN 6BJE
Enriched GO Terms of Interacting Partners?
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