MAP4K5 and COPS5

  • Data Source:
  • BioGRID (two hybrid)

MAP4K5

COPS5

Description mitogen-activated protein kinase kinase kinase kinase 5 COP9 signalosome subunit 5
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Cognitive performance ( 20125193)
  • Dupuytren's disease ( 28886342)
  • Heel bone mineral density ( 30598549)
  • Hemoglobin ( 32888494)
  • Hemoglobin levels ( 32327693)
  • Lupus nephritis in systemic lupus erythematosus ( 24925725)
  • Mean platelet volume ( 32888494)
  • Periodontal disease-related phenotype (Socransky) ( 24347629)
  • Red blood cell count ( 32888494)
Interacting Genes 13 interacting genes: ABL1 BCR COPS5 CRK CRKL GRB2 HCK NEDD4 SETDB1 SMURF1 TANK TRAF2 ZNF440 98 interacting genes: APCS ARFGAP1 ATM ATRN BCL2L14 BCL3 BRD4 BRSK2 CACNA1C CD274 CD93 CDKN1B CENPT CHUK COPS2 COPS3 COPS4 COPS6 COPS7A COPS7B COPS8 COPS9 CUL1 CUL2 CUL3 CUL4A CUL5 DDB1 DDO ERN1 ERRFI1 ESR1 F2RL1 GFER GFI1B GPS1 GTPBP3 HAND2 HIF1A HNF4A HNF4G HTR6 ITGB2 JUN JUND LASP1 MAP2K2 MAP3K11 MAP3K3 MAP3K7 MAP4K3 MAP4K5 MAPK14 MAPRE1 MAX MDC1 MDM2 MEF2C MEF2D MIF MTRES1 MYG1 NCOA1 NEDD8 NFKB1 NR4A2 NR4A3 OPRM1 PEA15 PGR PLAC8 PPARG PPOX PPP1CC PRDX2 PRKD1 PTGS2 RAD1 RAD9A RNF139 RORA S100A7 SHANK3 SHISA5 SMAD2 SMAD4 SMAD5 SPP1 SREBF2 TOP2A TP53 TXN TYK2 UCHL1 USP14 VTN WNK1 YWHAG
Entrez ID 11183 10987
HPRD ID 05374 06888
Ensembl ID ENSG00000012983 ENSG00000121022
Uniprot IDs B3KWC4 Q9Y4K4 A0A024R7W9 Q92905
PDB IDs 4D10 4D18 4F7O 4WSN 5JOG 5JOH 5M5Q 6R6H 6R7F 6R7H 6R7I
Enriched GO Terms of Interacting Partners?
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