GADD45G and ARPC5L

Data Source:
BioGRID (two hybrid, two hybrid)

		GADD45G	ARPC5L
Description		growth arrest and DNA damage inducible gamma	actin related protein 2/3 complex subunit 5 like
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Arp2/3 Protein Complex Focal Adhesion Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Binding	Molecular_function Protein Binding Actin Filament Binding
	Biological Process	Activation Of MAPKKK Activity Apoptotic Process Multicellular Organism Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of P38MAPK Cascade	Biological_process Cell Migration Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 28107422 26561523) General cognitive ability ( 29844566) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolic syndrome ( 31589552) Nonsyndromic cleft lip with cleft palate ( 28232668) Protein quantitative trait loci ( 18464913) Thyroglobulin plasma levels ( 30929638) Triglyceride levels ( 32203549 32154731)
Interacting Genes		72 interacting genes: ACTN1 AFAP1L1 APP ARPC5L BEND7 BLOC1S2 CCNB1 CDK1 CDKN1A CEP57L1 CFAP44 CNOT9 CRIP2 DCTN2 DDAH2 DDIT4L EEF1A1 EEF1G EIF3G ENKD1 ESR1 EZH2 FAM156A FAM156B GADD45B GADD45GIP1 GDF9 GRAMD4 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN NMB PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RASSF10 RBM48 RCN1 RDH13 REL RRP7A RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579 ZNF664 ZNF763	2 interacting genes: ARPC4 GADD45G
Entrez ID		10912	81873
HPRD ID		05383	12490
Ensembl ID		ENSG00000130222	ENSG00000136950
Uniprot IDs		O95257	A0A024R897 B3KPC7 Q9BPX5
PDB IDs		2WAL 3FFM	6YW6
Enriched GO Terms of Interacting Partners?
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