FAM114A2 and TTPA

Data Source:
BioGRID (two hybrid)

		FAM114A2	TTPA
Description		family with sequence similarity 114 member A2	alpha tocopherol transfer protein
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Late Endosome Cytosol
	Molecular Function	Protein Binding Purine Nucleotide Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding
	Biological Process	Biological_process	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer
Pathways		Signaling by BRAF and RAF fusions	Vitamin E
Drugs
Diseases			Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS		Apolipoprotein A1 levels ( 32203549) Red cell distribution width ( 32888494 28957414)
Interacting Genes		11 interacting genes: APP GAD2 MIEF2 NDUFV2 PILRA PTPN9 RAB2A RAB2B SH3GLB1 TBRG4 TTPA	46 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52
Entrez ID		10827	7274
HPRD ID		12831	02685
Ensembl ID		ENSG00000055147	ENSG00000137561
Uniprot IDs		A0A140VKG4 B3KTE4 B4DQT0 E7ESJ7 I6L9D5 Q9NRY5	P49638
PDB IDs			1OIP 1OIZ 1R5L 5MUE 5MUG
Enriched GO Terms of Interacting Partners?
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