TTPA and CMTM4

Data Source:
BioGRID (two hybrid)

		TTPA	CMTM4
Description		alpha tocopherol transfer protein	CKLF like MARVEL transmembrane domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Late Endosome Cytosol	Integral Component Of Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Vitamin E Binding Phosphatidylinositol-3,4-bisphosphate Binding Lipid Transfer Activity Phosphatidylinositol Bisphosphate Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Response To Nutrient Response To PH Developmental Process Vitamin E Metabolic Process Vitamin Transport Intracellular PH Reduction Negative Regulation Of Cell Death Intermembrane Lipid Transfer
Pathways		Vitamin E
Drugs
Diseases		Ataxia with isolated vitamin E deficiency (AVED); Friedreich-like ataxia
GWAS
Interacting Genes		46 interacting genes: AGTRAP APOA5 APOC2 APP ARFIP2 ARMC12 BIRC7 CISD2 CMTM4 CMTM5 COQ3 CYSRT1 DGAT2L6 DHODH FADS6 FAM114A2 FAM25A FAM25C FAM25G FGF14 FKBP7 GOLGA2 HSD17B11 JOSD2 KRTAP10-7 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 LEUTX MAL2 MRM1 NBPF19 NDUFA7 NOTCH2NLA PEX12 REEP2 RPRM SAR1A SCAMP1 SCAMP5 SDR16C5 SLC35E3 SYNGR3 THAP4 TPD52	20 interacting genes: APOA4 APPL1 COQ8A DAPK1 DGCR6L DIABLO HSBP1L1 MIDN MRPL2 PBX3 PTPN9 SMG9 SNX1 SPG21 SSX3 STAR TBRG4 TCEA2 TTPA ZFYVE21
Entrez ID		7274	146223
HPRD ID		02685	07435
Ensembl ID		ENSG00000137561	ENSG00000183723
Uniprot IDs		P49638	Q8IZR5
PDB IDs		1OIP 1OIZ 1R5L 5MUE 5MUG
Enriched GO Terms of Interacting Partners?
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