TACC2 and YEATS4

Data Source:
HPRD (in vivo, in vitro)

		TACC2	YEATS4
Description		transforming acidic coiled-coil containing protein 2	YEATS domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Plasma Membrane	Nucleus Nucleoplasm Nuclear Matrix Nuclear Membrane NuA4 Histone Acetyltransferase Complex
	Molecular Function	Nuclear Hormone Receptor Binding	Structural Constituent Of Cytoskeleton Protein Binding Protein C-terminus Binding Lysine-acetylated Histone Binding Modification-dependent Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Population Proliferation Cerebral Cortex Development	Mitotic Cell Cycle Cytoskeleton Organization Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			HATs acetylate histones Activation of the TFAP2 (AP-2) family of transcription factors
Drugs
Diseases
GWAS		Hepcidin/ferritin ratio ( 27846281) Metabolite risk score for predicting weight gain ( 31560688) Myopia (pathological) ( 23049088) Normal facial asymmetry (angle of surface orientation score) ( 30631343) Obesity-related traits ( 23251661) Opioid dependence ( 31250797) Pulse pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Total body bone mineral density ( 29304378)	Complete remission in asthma ( 29786918) Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454) Height ( 31562340 18391951) Metabolite levels ( 23823483) Response to antidepressants (symptom remission) ( 29160301) Response to diuretic therapy ( 18591461) Response to SSRI in MDD or conscientiouness ( 29559929) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		15 interacting genes: AURKC BORCS6 CLK2 CLVS2 CREBBP EP300 GRAMD4 HMG20B KAT2A KAT2B PPP1CC RXRB SMARCB1 TGM1 YEATS4	17 interacting genes: ANKK1 CEP162 FRMD4A GTF2F2 H3C1 MLLT10 MRGBP MYCN NUMA1 PFDN1 RNF8 SMARCB1 TACC1 TACC2 TFAP2B TPM1 TRIM54
Entrez ID		10579	8089
HPRD ID		05600	03666
Ensembl ID		ENSG00000138162	ENSG00000127337
Uniprot IDs		B2RWP4 B7ZMJ9 D6RAA5 O95359 Q4VXL4 Q4VXL8	F8W0J4 O95619
PDB IDs			5VNA 5VNB 5XTZ 5Y8V
Enriched GO Terms of Interacting Partners?
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